MYCOPLASMA CHROMOSOMAL TRANSFER: A DISTRIBUTIVE, CONJUGATIVE PROCESS CREATING AN INFINITE VARIETY OF MOSAIC GENOMES

Mycoplasma Chromosomal Transfer: A Distributive, Conjugative Process Creating an Infinite Variety of Mosaic Genomes

The capacity of Mycoplasmas basket to engage in horizontal gene transfers has recently been highlighted.Despite their small genome, some of these wall-less bacteria are able to exchange multiple, large portions of their chromosome via a conjugative mechanism that does not conform to canonical Hfr/oriT models.To understand the exact features underly

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Thioredoxin peroxidase secreted by Echinococcus granulosus (sensu stricto) promotes the alternative activation of macrophages via PI3K/AKT/mTOR pathway

Abstract Background Larvae of Echinococcus granulosus (sensu lato) dwell in host organs for a long time but elicit only a mild inflammatory response, which indicates that the resolution of host inflammation is necessary for parasite survival.The recruitment of alternatively activated macrophages (AAMs) has been observed in a variety of helminth inf

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Potential impact of miR-137 and its targets in schizophrenia

The significant impact of microRNAs (miRNAs) on disease pathology is becoming increasingly evident.These small non-coding RNAs have the ability to post-transcriptionally silence the expression of thousands of genes.Therefore, dysregulation of even a single miRNA could confer a large polygenic effect.Schizophrenia is a genetically complex illness th

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